Duke Endowment disbursed $14.4 million to relief agencies in western North Carolina and Upstate South Carolina.
Other grantees include the United Way of Greenville County, S.C.
The Community Foundation of Western North Carolina received $5 million, while the One SC Fund received $3 million.
The American Red Cross received $1 million to support food and shelter needs.
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Mozambikes, a for-profit social venture, was formed during a road trip across Mozambique. The founders of Mozambikes aim to improve the quality of life among rural Mozambicans by providing low-cost, efficient personal transportation.